Pharmacokinetics

Dr. Victor S. Blanchette
MD, FRCP, FRCP(C)

Dr. Victor Blanchette is Medical Director of the Pediatric Thrombosis and Hemostasis Program in the Division of Haematology/Oncology at the Hospital for Sick Children in Toronto, and Professor of Pediatrics at the University of Toronto, Canada. He is a Senior Associate Scientist in the Research Institute of the Hospital for Sick Children, and a Clinician Investigator in the Hospital’s Department of Paediatrics.

After completing his medical training at the University of Cambridge and St Bartholomew's Hospital in the United Kingdom, Dr Blanchette pursued subspecialty training in pediatrics at Johns Hopkins Hospital in Baltimore, Maryland, USA followed by fellowship training in pediatric hematology/oncology at McMaster University Medical Centre in Hamilton, Ontario, Canada.

Dr Blanchette's research interests are in the area of the congenital and acquired bleeding disorders of children. He is Director of the Pediatric Comprehensive Care Hemophilia Program at the Hospital for Sick Children, and Chairman of the Factor Prophylaxis Subcommittee of the Association of Hemophilia Clinic Directors of Canada (AHCDC). He is also Chair of the Canadian Pediatric Thrombosis and Hemostasis Network (CPTHN) and of the International Prophylaxis Study Group (IPSG). Dr Blanchette is an elected fellow of the Royal College of Physicians and Surgeons of the United Kingdom.

Key Publications
  1. Blanchette VS, Manco-Johnson M, Santagostino E, Ljung R:  Optimizing factor prophylaxis for the haemophilia population: where do we stand?  Haemophilia 2004:10 Suppl 4: pp 97-104
  2. Manco-Johnson MJ, Pettersson H, Petrini P, Babyn PS, Bergstrom B-M, Bradley C-S,     Doria AS, Feldman BM, Funk S, Hilliard P, Kilcoyne R, Lundin B, Nuss R, Rivard G,   Schoenmakers MAGC, Van Den Berg M, Wiedel J, Zourikian N, Blanchette VS: Physical therapy and imaging outcome measures in a haemophiliia population treated with factor prophylaxis: current status and future directions. 
  3. van den Berg HM, Dunn A, Fischer K, Blanchette VS: Prevention and treatment of musculoskeletal disease in the haemophilia population: role of prophylaxis and synovectomy.   Haemophilia 2006: 12 Suppl 3: pp 159-68
  4. Blanchette VS:  Prophylaxis in the haemophilia population.  Haemophilia 2010:16(Suppl 5):pp 181-188,  July 2010. 

Current Positions/Chairs:

  • Medical Director
    The Pediatric Thrombosis and Hemostasis Program in the Division of Haematology/Oncology at the Hospital for Sick Children.
  • McCaig Magee Medical Director
    Centre for Global Child Health, Sickkids-Caribbean Initiative
  • Professor
    Professor of Pediatrics at the University of Toronto, Canada
  • Senior Associate Scientist
    The Research Institute of the Hospital for Sick Children, and a Clinician Investigator in the Hospital’s Department of Paediatrics
  • Chairman
    The Factor Prophylaxis Subcommittee of the Association of Hemophilia Clinic Directors of Canada (AHCDC)
  • Chair
    The Canadian Pediatric Thrombosis and Hemostasis Network (CPTHN)
  • Chair
    The International Prophylaxis Study Group- Executive Committee

Key Institutions

  • The Hospital for Sick Children
    Department of Paediatrics, Division of Haematology/Oncology, and The Research Institute
    Toronto , Canada
  • The University of Toronto
    Department of Paediatrics
    Toronto , Canada

Research Interests

  • Congenital and acquired bleeding disorders of children
  • Clinical and basic science studies of the immune thrombocytopenias in childhood
  • Development of paediatric transfusion medicine guidelines

Achievements

  • Inaugural Holder- Women's Auxillary Millenium Chair in Paediatric Haematology/ Oncology, Hospital for Sick Children
  • Elected Fellow- Royal College of Physicians, UK (1990)
  • Canadian Pediatric Society 2009 Alan Ross Award
  • Canadian Blood Services 2010 Lifetime Achievement Award
  • American Society of Pediatric Hematology/ Oncology 2012 Distinguished Career Award

Publications

July 23, 2011

An MRI scale for Assessment of Hemophilic Arthropathy from the International Prophylaxis Study Group

The XXIII International Society on Thrombosis & Haemostasis Congress (July 23-28, 2011 – Kyoto, Japan).
Authors
Lundin B, Manco-Johnson ML, Ignas D, Moineddin R , Babyn P, Blanchette VS, Dunn A , Gibikote SV, Keshava SN, Ljung R, Manco-Johnson MJ ,Miller SF, Rivard GE, Doria AS on behalf of the International Prophylaxis Study Group.
Citation
Award: Red ribbon award for the top ranked 20% of poster presentations.
July 1, 2011

An MRI scale for assessment of hemophilic arthropathy from the International Prophylaxis Study Group

Haemophilia 2012 Nov; 18 (6):962-70
Authors
Lundin B, Manco-Johnson ML, Ignas DM, Moineddin R, Blanchette VS, Dunn AL, Gibikote SV, Keshava SN, Ljung R, Manco-Johnson MJ,Miller SF, Rivard GE, Doria AS on behalf of the International Prophylaxis Study Group.
Citation
Accepted to the XXIII International Society on Thrombosis and Haemostasis Congress (July 23-28, 2011 – Koyoto, Japan).
January 28, 2011

Validation of a new pediatric joint scoring system from the International Hemophilia Prophylaxis Study Group: Validity of the Hemophilia Joint Health Score (HJHS).

Authors
Feldman BM, Funk S, Bergstrom B-M, Zourikian N, Hilliard P, van der Net J, Engelbert RHH, Petrini P, van den Berg M , Manco-Johnson M, Rivard GE, Abad A, and Blanchette VS.
Citation
Arthritis Care & Research 2011 Feb; 63 (2):223-30.
June 1, 2008

Musculoskeletal measurement tools from the International Prophylaxis Study Group (IPSG)

The XXVIII World Federation of Hemophilia Congress (June 1-5, 2008 – Istanbul, Turkey) Invited symposium as part of the scientific program of the WFH Congress (Chair: Dr. Victor Blanchette). Dr. Victor Blanchette, Overview of the International Prophylaxis Study Group, Ms. Sharon Funk and Dr. Brian Feldman, Hemophilia Joint Health Score. Dr. Andrea Doria and Dr. Bjorn Lundin, Role of MRI for detection of early arthropathy: A proposed new International MRI Score.
Authors
Feldman BM, Funk S, Lundin B, Doria AS, Blanchette V.
Citation
May 16, 2008

Musculoskeletal measurement tools from the International Prophylaxis Study Group (IPSG).

Authors
Feldman BM, Funk S, Lundin B, Doria AS, Ljung R, and Blanchette V.
Citation
Haemophilia 2008, 14 (Suppl. 3), 162-169.
September 10, 2007

The economics of haemophilia prophylaxis: governmental and insurer perspectives. Proceedings of the Second International Prophylaxis Study Group (IPSG) Symposium.

Authors
Feldman BM, Aledort L, Bullinger M, Delaney FM, Doria AS, Funk S, Giangrande P, Lundin B, Manco-Johnson M, Miners A, Scriba PC, Srivastava A, Schramm W and Blanchette VS.
Citation
Haemophilia 2007 Nov; 13 (6): 745-749.
May 21, 2006

MRI Scoring Systems in hemophilic arthropathy

The XXVII World Federation of Hemophillia Congress (May 21-25, 2006 - Vancouver, Canada).
Authors
Lundin B, Doria A, Kilcoyne R, Babyn P, Miller S, Nuss R, Rivard G, Pettersson H, and Blanchette V.
Citation
May 21, 2006

Discriminant validity and reliability of the Compatible MRI Scoring System for assessment of hemophilic arthropathy in children

The XXVII World Federation of Hemophillia Congress (May 21-25, 2006 - Vancouver, Canada).
Authors
Doria AS, Lundin B, Kilcoyne RF, Babyn PS, Miller SW, Nuss R, Rivard G, Pettersson HT, and Blanchette V.
Citation
May 10, 2006

Discriminant validity and reliability of the Compatible MRI Scoring System for assessment of hemophilic arthropathy in children.

Authors
Doria A, Lundin B, Kilcoyne RF, Babyn PS, Miller SW, Pettersson HT, and Blanchette V.
Citation
Haemophilia 2006 May; 12 (S2): # 22 S 686
May 10, 2006

MRI scoring systems in hemophilic arthropathy.

Authors
Lundin B, Doria A, Kilcoyne R, Babyn P, Miller S, Nuss R, Rivard G, Pettersson H, and Blanchette V.
Citation
Haemophilia 2006 May; 12 (S2): # 22 S 685
March 4, 2006

Are randomized clinical trials the only truth? Not always

Authors
Aledort L, Ljung R, and Blanchette V on behalf of the International Prophylaxis Study Group (IPSG)
Citation
Journal of Thrombosis and Haemostasis 2006 Mar; 4 (3): 503 - 504.
September 9, 2005

Radiological Scoring in Hemophilic Arthropathy

The IX World Federation of Hemophilia Musculoskeletal Congress (September 9-11, 2005 - Istanbul, Turkey).
Authors
Lundin B and Blanchette V on behalf of the IPSG MRI Working Group
Citation
January 21, 2005

Proceedings of the International Haemophilia Prophylaxis Study Group Meeting November 2003, Montreal, PQ, Canada.

Authors
Feldman BM, Babyn P, Doria AS, Heijnen L, Jacobson J, Kilcoyne R, Lundin B, Manco-Johnson M, McLimont M, Petrini P, Pettersson H, and Blanchette VS on behalf of the IPSG.
Citation
Haemophilia 2005 Jan; 11: 58 – 63.
October 17, 2004

Physical therapy and imaging outcome measures in a haemophilia population treated with factor prophylaxis: current status and future directions

The XXVI World Federation of Hemophillia Congress (October 17-21, 2004 - Bangkok, Thailand). Invited symposium as part of the scientific program of the WFH Congress (Chairs: Dr. Victor. Blanchette and Dr. Marilyn Manco-Johnson). Dr. Victor Blanchette, Opening remarks. Dr. Bjorn Lundin, X-ray.MRI Scoring Systems: Overview. Dr. Andrea Doria, Compatible Scales for progressive and additive MRI of hemophilic arthropathy. Dr. Pia Petrini, Physical Therapy Scale Overview. Dr. Brian Feldman, Reliability of the Hemophilia Joint Health Score (HJHS).
Authors
Doria AS, Feldman BM, Lundin B, and Blanchette VS on behalf of the IPSG
Citation
October 8, 2004

Physical therapy and imaging outcome measures in a haemophilia population treated with factor prophylaxis: current status and future directions.

Authors
Manco-Johnson MJ, Pettersson H, Petrini P, Babyn PS, Bergstrom B-M, Bradley CS , Doria AS, Feldman BM, Funk S, Hilliard P, Kilcoyne R, Lundin B, Nuss R, Rivard G, Schoenmakers MA, van den berg M, Wiedel J, Zourikian N, and Blanchette VS.
Citation
Haemophilia 2004 Oct; 10 (S4):88 – 93.